王霞

助理教授(教学)

教育背景

博士 (香港中文大学)

硕士 (华中科技大学)

学士 (武汉科技大学)

研究领域
细胞-细胞外基质相互作用,神经嵴细胞分化,胚胎发育,器官形成。
电子邮件
wangxia@cuhk.edu.cn
个人简介

王霞博士自2023年开始在香港中文大学(深圳)医学院担任助理教授(教学)一职。她于2009年在香港中文大学获得博士学位。在2010年至2017年期间,她先后曾在香港中文大学和Thomas Jefferson University进行博士后培训和担任副研究员参与科研工作。2017年至2023年期间,曾在深圳大学医学院担任助理教授。她的研究主要集中在以转基因小鼠和斑马鱼等模式生物作为研究对象,探究细胞间和细胞与细胞外基质间相互作用,及其调节神经嵴细胞的发育并参与头面部、心血管系统和胃肠道等器官的形成过程的分子机制。她在Gastroenterology, Development, Journal of Dental Research, and Developmental Biology等知名期刊上发表了多篇论文。她的研究项目获得了包括国家自然科学基金青年项目、广东省自然科学基金项目、深圳市科技创新计划以及美国心脏协会博士后奖学金等的支持。

学术著作
  1. Wang K, Wang X, Zhang M, Ying Z, Zu Z, Tam KY, Li C, Zhou G, Gao F, Zeng M, Sze SC, Wang X#, Sha O#. Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma. International Journal of Molecular Sciences. 2023 Jan 11;24(2):1416. doi: 10.3390/ijms24021416.
  2. Lin W*, Gao F*, Wang X*, Qin N, Chen X, Tam K, Zhang C, Zhang M#, Sha O#. The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection. Frontiers in Cellular Neuroscience. 2023 Jan 4;16:1006977.
  3. Wang X, Liang YL, Zhu Z, Li WQ, Shi B, Deng YQ, Li CM#, Sha O#. Fibronectin regulates the 3rd pharyngeal pouch patterning and morphogenesis. Journal of Dental Research. 2022 Mar 8;220345221078775. doi: 10.1177/00220345221078775.
  4. Chi H*, Hao Y*, Wang X*, Tang L, Deng YQ, Chen XX, Gao F, Sha O#, Jin G#. A Therapeutic Whole-Tumor-Cell Vaccine Covalently Conjugated with a TLR7 Agonist. Cells. 2022 Jun 21;11(13):1986. doi: 10.3390/cells11131986.
  5. Huang T, Hou Y, Wang X, Wang L, Yi C, Wang C, Sun X, Tam P, Ngai S, Sham S, Burns A, Chan WY. Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects. Gastroenterology, 162(1):179-192,2022.01. doi: 10.1053/j.gastro.2021.08.029.
  6. Tam WY, Wang X, Cheng ASK, Cheung KK. In Search of Molecular Markers for Cerebellar Neurons. International Journal of Molecular Sciences. 2021 Feb 12;22(4):1850. doi: 10.3390/ijms22041850.
  7. Warkala M, Chen DY, Ramirez A, Jubran A, Schonning M, Wang X, Zhao H and Astrof S. Cell-Extracellular Matrix Interactions Play Multiple Essential Roles in Aortic Arch Development. Circulation Research,128(3):e27-e44,2021.02.
  8. Wang X, Li C, Zhu Z, Yuan L, Chan WY, Sha O#.  Extracellular Matrix Remodeling During Palate Development. Organogenesis. 2020 Apr 2;16(2):43-60. doi: 10.1080/15476278.2020.1735239.
  9. Ying Z, Yang J, Li W, Wang X, Zhu ZY, Jiang WP, Li CM#, Sha O#, Astrin: A Key Player in Mitosis and Cancer. Frontiers in cell and developmental biology,8:866,2020.08.
  10. Wang X*, Chen D*, Chen K*, Jubran A, Ramirez AJ and Sophie Astrof. Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Developmental Biology. 2017 Jan 15; 421 (2): 108-117. doi: 10.1016/j.ydbio.2016.12.010. doi: 10.1016/j.ydbio.2016.12.010.
  11. Xu X, Liang D, Zhang J, Ji X, Hu H, Sun Y, Jiang T, Wang X, Hu P, Xu X, Generation of integration-free induced pluripotent stem cell line (NJMUi001-A) from a phenylketonuria patient. Stem Cell Research, 25, 2017.12.
  12. Wang X and Astrof S. Neural crest cell-autonomous roles of fibronectin in cardiovascular development. Development. 2016 Jan 1; 143(1): 88-100. doi: 10.1242/dev.125286.
  13. Chen D*, Wang X*, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S. Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.  Developmental Biology. 2015 Nov 15; 407(2): 195-210. doi: 10.1016/j.ydbio.2015.09.016.
  14. Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S. Mesodermal expression of integrin a5b1 regulates neural crest development and cardiovascular morphogenesis. Developmental Biology. 2014 Nov 15;395(2):232-44. doi: 10.1016/j.ydbio.2014.09.014.
  15. Wang X, Chan AKK, Sham MH, Burns AJ and Chan WY. Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo. Gastroenterology. 2011 Sep, 141 (3), 992-1002. doi: 10.1053/j.gastro.2011.06.002.