博士（军事科学院军事医学研究院）

张政教授于1999年本科毕业于空军军医大学，并于2005年获得军事科学院军事医学研究院博士学位。是“国家杰出青年基金获得者”和“国家科技部重点研发计划课题负责人”，先后获得“第二届创新争先奖状获得者”、“中国免疫学青年学者奖”、 “国家百千万人才工程有突出贡献中青年专家”等。主要围绕病原感染免疫致病机制和免疫治疗策略深入开展研究，获得国家科技进步二等奖、广东省科技进步特等奖、中华医学科技奖和教育部科技进步一等奖等。以第一/通讯作者（含共同）在Nature，Cell，Nat Med，JAMA，Nat Commun ，Sci Adv，J Clin Invest等发表SCI论文90多篇，H指数55。入选中国研究型医院学会肝病学分会和结核病学分会副主任委员、中国免疫学会感染免疫分会委员等。多次在欧洲免疫学年会、美国免疫学年会、亚太地区肝病年会、中国免疫学大会发言。以第一课题负责人承担国家重点研发计划、传染病重大专项课题、973项目子课题、国家自然科学基金重大研究计划、优秀青年基金、面上项目等16项。

1.    Ju B#, Zhang Q#, Ge S, Wang R, Yu J, Shan S, Zhou B, Song S, Tang X, Yu J, Ge J, Lan J, Yuan J, Wang H, Zhao J, Zhang S, Wang Y, Shi X, Liu L, Wang X, Zhang Z*, Zhang L*. Potent human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 2020, 584(7819):115-119.
2.    Zhang Q#, Ju B#, Ge J#, Chan JF#, Cheng L#, Wang R#, Huang W#, Fang M, Chen P, Zhou B, Song S, Shan S, Yan B, Zhang S, Ge X, Yu J, Zhao J, Wang H, Liu L, Lv Q, Fu L, Shi X, Yuen KY, Liu L, Wang Y*, Chen Z*, Zhang L*, Wang X*, Zhang Z*. Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Communications, 2021, 12:4210.
3.    Bost P#, Giladi A#, Liu Y#, Bendjelal Y, Xu G, David E, Blecher-Gonen R, Cohen M, Medaglia C, Zhang S, Schwikowski B*, Zhang Z*, Amit I*. Host-viral infection maps reveal signatures of severe COVID-19 patients. Cell, 2020, 181(7):1475-1488. 
4.    Liao M#, Liu Y#, Yuan J#, Wen Y, Xu G, Zhao J, Cheng L, Li J, Wang X, Wang F, Liu L*, Ido A*, Zhang S*, Zhang Z*. Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19. Nat Med, 2020, 26(6):842-844.
5.    Zhao J#, Yuan Q#, Wang H#, Liu W#, Liao X#, Su Y#, Wang X, Yuan J, Li T, Li J, Qian S, Hong C, Wang F, Liu Y, Wang Z, He Q, Li Z, He B, Zhang T, Ge S*, Liu L*, Zhang J*, Xia N, Zhang Z*. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis, 2020, 71(16):2027-2034. 
6.    Tang X, Zhang S, Peng Q, Ling L, Shi H, Liu Y, Cheng L, Xu L, Cheng L, Chakrabarti LA, Chen Z, Wang H, Zhang Z*. Sustained IFN-I Stimulation Impairs MAIT Cell Responses to Bacteria by Inducing IL-10 during chronic HIV-1 Infection. Sci Adv, 2020,6(8):eaaz0374. 
7.    Zhang Z#*, Cheng L#, Zhao J#, Li G, Zhang L, Chen W, Nie W, Reszka-Blanco N, Wang FS*, Su L*. Plasmacytoid dendritic cells promote HIV-1-induced group-3 innate lymphoid cell depletion. J Clin Invest, 2015, 125(9):3692–3703.
8.    Xu X#, Shang Q#, Chen X#, Nie W, Zou Z, Huang A, Meng M, Jin L, Xu R, Zhang JY, Fu J, Wang L, Tang Z, Xie Y, Yang X, Zhang Z*, Wang FS*. Reversal of B-cell hyperactivation and functional impairment is associated with HBsAg seroconversion in chronic hepatitis B patients. Cell Mol Immunol, 2015, 12: 309-316.
9.    Zhang Z#, Zhang S#, Zou Z#, Shi J, Zhao J, Fan R, Qin E, Li B, Li Z, Xu X, Fu J, Zhang J, Gao B, Tian Z,Wang FS*. Hyper–Cytolytic Activity of Hepatic Natural Killer Cells Correlates with Liver Injury in Chronic Hepatitis B Patients. Hepatology, 2011, 53(1): 73-85. 
10.    Zhang Z#, Zhang JY#, Wherry EJ, Jin B, Xu B, Zou, ZS, Zhang SY, Li BS, Wang HF, Wu H, Fu YX, Wang FS. Dynamic programmed death-1 expression on virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. Gastroenterology, 2008, 134: 1938-1949.