王明华

临床客座助理教授

教育背景

博士(重庆医科大学)
学士(重庆医科大学)

研究领域
子宫内膜异位症机制及相关肿瘤、EBV与淋巴瘤; 胶质瘤的发病机制及靶向治疗
邮箱
wangminghua@cuhk.edu.cn
个人简介

王明华临床客座助理教授于1995年毕业于重庆医科大学临床医学专业,2008年在重庆医科大学大学获得博士学位,2020年加入香港中文大学(深圳)第二附属医院。研究领域涉及子宫内膜异位症机制及相关肿瘤、EBV与淋巴瘤; 胶质瘤的发病机制及靶向治疗等,并发表了大量关于上述领域的文章。王明华临床客座助理教授自2014年起为中华医学会病理学分会第十一、十二和十三届乳腺疾病学组委员、中华医学会海南省病理学分会副主任委员(2019-2022)、中国医师协会脑胶质瘤专业委会第一和第二届分子诊疗专业委员会(2017-2022)、深圳市病理医师协会副会长(2023-2026)和深圳市第六届常务委员(2024-2028)。

学术著作

1.Chen H, Wang M, Zhang Z, Lin F, Guo B, Lu Q, Lash GE, Li P. Oxidative stress drives endometrial fibrosis via TGF-β1/MAPK signaling pathway in breast cancer. FASEB J. 2024 Nov 30;38(22):e70172. doi: 10.1096/fj.202401257RR. PMID: 39548950.
2.Ren X, Yao B, Zhou X, Nie P, Xu S, Wang M, Li P. Caulerpin alleviates cyclophosphamide-induced ovarian toxicity by modulating macrophage-associated granulosa cell senescence during breast cancer chemotherapy. Int Immunopharmacol. 2024 Oct 31;143(Pt 3):113513. doi: 10.1016/j.intimp.2024.113513. Epub ahead of print. PMID: 39486187.
3.Chen Z, Wang M, Yang P, Yao B, Shuai H, Li P. Exaggerated placental site in a cesarean scar: Misdiagnosed as gestational trophoblastic neoplasia: A case report. Exp Ther Med. 2024 May 23;28(1):298. doi: 10.3892/etm.2024.12587. PMID: 38868614; PMCID: PMC11168028.
4.Li M, Wang M, Huang J, Tang S, Yang J, Xu Z, Xu G, Chen X, Liu J, Yang C. High-performance pyrite nano-catalyst driven photothermal/chemodynamic synergistic therapy for Osteosarcoma. J Nanobiotechnology. 2024 Apr 1;22(1):141. doi: 10.1186/s12951-024-02419-2. PMID: 38561739; PMCID: PMC10983657.
5.Xiao H, Hu L, Tan Q, Jia J, Xie P, Li J, Wang M. Transcriptional profiles reveal histologic origin and prognosis across 33 The Cancer Genome Atlas tumor types. Transl Cancer Res. 2023 Oct 31;12(10):2764-2780. doi: 10.21037/tcr-23-234. Epub 2023 Sep 20. PMID: 37969389; PMCID: PMC10643977.
6.Wang M, Liu J, Hu B, Wang S, Xie P, Li P. Appendiceal perforation secondary to endometriosis with intestinal metaplasia: A case report. Exp Ther Med. 2023 Apr 19;25(6):262. doi: 10.3892/etm.2023.11961. PMID: 37206544; PMCID: PMC10189722.
7.Zhong H, Wang M, Zhang H, Huang Z, Zou B, Zou G, Xie N, Liang Y, Zhu Y, Ma W. Gout of feet and ankles in different stages: The potentiality of a new semiquantitative DECT scoring system in monitoring urate deposition. Medicine (Baltimore). 2023;102(3): e32722.
8.Zhang W, Liu R, Chen Y, Wang M, Du J. Crosstalk between Oxidative Stress and Exosomes. Oxid Med Cell Longev. 2022 Aug 30;2022:3553617. doi: 10.1155/2022/3553617. PMID: 36082080; PMCID: PMC9448575.
9.Gao L, Chen H, Liu J, Wang M, Lin F, Yang G, Lash GE, Li P. Extravillous trophoblast invasion and decidualization in cesarean scar pregnancies. Acta Obstet Gynecol Scand. 2022 Aug 4. doi: 10.1111/aogs.14435. Epub ahead of print. PMID: 35924378.
10.Bai S, Wang Z, Wang M, Li J, Wei Y, Xu R, Du J. Tumor-Derived Exosomes Modulate Primary Site Tumor Metastasis. Front Cell Dev Biol. 2022 Mar 2;10:752818. doi: 10.3389/fcell.2022.752818. PMID: 35309949; PMCID: PMC8924426.
11.Yang B, Liao H, Wang M, Long Q, Zhong H, Luo L, Liu Z, Cheng X. Kimura's disease successively affecting multiple body parts: a case-based literature review. BMC Ophthalmol. 2022 Apr 2;22(1):154. doi: 10.1186/s12886-022-02378-y. PMID: 35366827; PMCID: PMC8977031.
12.Wang M, Wu Y, He Y, Liu J, Chen Y, Huang J, Qi G, Li P. SIRT1 upregulation promotes epithelial-mesenchymal transition by inducing senescence escape in endometriosis. Sci Rep. 2022 Jul 19;12(1):12302. doi: 10.1038/s41598-022-16629-x. PMID: 35853978.
13.Wang MH, Zheng J, Luo ZF, Fang DD, Weng Y.  biphenotypic sinonasal sarcoma, case report. J Diag Pathol, 2018,25(11):779-781. (Chinese)
14.Wang MH, Luo ZF, Chen MJ, Wu WT, Zheng YF, Yang ZY, Weng Y. Clinicopathological features of extraocular NK/T cell lymphoma (nasal type) in 24 young adults. J Clin Exp Patho, 2018,34(3):337-340. (Chinese)
15.Wang MH, Luo ZF, Meng QP, Chen XY, Chen MJ, Xie N, Zhang X, Huang YS, Weng Y. Scanning of differentially expressed genes of EBV-transformed B lymphocyte. Guangdong  Medical Journal, 2017,38(19):2913-2918. (Chinese)
16.Wang MH, Luo ZF, Meng QP, Chen XY, Chen MJ, Xie N, Zhang X, Huang YS, Weng Y.  Expression of CD5 and CD43 in diffuse large B cell and relationship with prognosis. (Chinese)
17.Wang MH, Luo ZF, Meng QP, Chen XY, Chen MJ, Xie N, Zhang X, Huang YS, Weng Y. Expression and pathological significance of AID protein in diffuse large B cell lymphoma. China Tropical Medicine, 2015,12(2):197-199. (Chinese)
18.Wang MH, Luo ZF, Meng QP, Chen XY, Chen MJ, Xie N, Zhang X, Huang YS, Weng Y. significance of c-MYC/IGH translocation detected by fluorescence in situ hybridization (FISH) in lymphoproliferative disease. Journal of Hainan Medical University. 2014,12(20):1601-1603. (Chinese)
19.Ming Hua Wang, Chen Li Lin, Ji Jun Zhang, Ze Ping Weng, Ting Hu, Qiang Xie, Xue Yun Zhong. Role of PTEN on CT inducing glioma cell SWO-38 differentiation. Molecular Medicine Reports, 2013, 17 (6): 1912-1918.
20.Wang MH, Weng Y, Luo ZF, Wu YY, Wang LH. The differentiation features of diffuse large B cell lymphoma in nodal and extranodal. Guangdong Medical Journal, 2011,32(16): 2183-2185. (Chinese)
21.Wang MH, Weng Y, Zheng J, Luo ZF. The clinicopathological features of lymphoma in Hainan area. Acta academiae medicinae militaris tertiae .2011,33(5): 501. (Chinese)
22.Wang MH, Zheng J, Ding LL, Luo ZF, Wang LH, Wu YY. Pathological features of triple-negative invasive ductal carcinoma of breast. Journal of Hainan Medical University, 2010,16(11):1409-1411. (Chinese)
23.Wang MH, Luo ZF, Wang JL. Pathological analysis of 29 cases with MALT lymphoma. Journal of Hainan Medical University, 2010,16(12):1562-1565. (Chinese)
24.Chen Li Lin, Ming Hua Wang, Yan Fang Qin, Mao Fang, Bin Bin Xie, Xue Yun Zhong. Differentiation of SWO-38 glioma cells induced by CDA-2 is mediated by peroxisome proliferator-activated receptor γ. J Neurooncol, 2009, 95(1): 29-36.