LI, Chenzhong

X.Q. Deng Presidential Chair Professor, Programme Coordinator of MPhil-PhD Programme in Biomedical Science and Engineering
World's Top 2% Scientist; Member of the Canadian Academy of Engineering, Member of the National Academy of Inventors, AIMBE fellow of the American Academy of Medical Biological Sciences

X.Q. Deng Presidential Chair Professor, Professor

Education Background

Ph.D. (Kumamoto University)

M.S. (Kumamoto University)

B.S. (North China University of Science and Technology)

Research Field
Bioinstrumentation, Bioelectronics, Analytical Chemistry, and BioMEMS, with an emphasis on the development of biosensors including lab-on-a-chip, portable devices and optical probes.
Personal Website
Email
lichenzhong@cuhk.edu.cn
Biography

Prof. Chenzhong LI is a X.Q. Deng Presidential Chair Professor at the Chinese University of Hong Kong, Shenzhen, the editor-in-chief of the international flagship academic journal Biosensor and Bioelectronics (IF13), the deputy editor-in-chief of RESEARCH (IF11) sponsored by the China Association for Science and Technology, and the journal Technology and Innovation of the National Academy of Inventors. Editor-in-Chief of Journal.

Prof. Chenzhong LI is a Full-time Professor of School of MEDICINE, The Chinese University of Hong Kong, Shenzhen. Prof. LI obtained a M.S. degree and a Ph.D. degree both from Kumamoto University. After his Ph.D. study, he got postdoctoral training at the University of British Columbia and University of Saskatchewan. Then he started his career as a Research Officer at the Biotechnology Research Institute (Montreal) of Canada National Research Council. In 2006, he moved to USA and started to work at the Department of Biomedical Engineering in Florida International University for about 15 years, initially serving as an Assistant Professor, later as an Associate Professor and Director (with tenure), and finally as a Full Professor. From 2017 to 2020, he was selected to serve as the project director of the National Foundation for the United States for three years, engaged in the strategic formulation of the US national scientific research plan, assisting in the review and management of innovation and transformation seed funds for small and medium-sized enterprises, and scientific research funds in the field of biochips and sensors, also the management and approval of scientific research projects. It also cooperated with other disciplines within the National Foundation of the United States, the U.S. Department of Defense, the Advanced Technology Development Agency, the U.S. Department of Agriculture, DARPA, the Department of Health and Human Services, the U.S. Environmental Protection Agency, the Space Administration, and the National Administration of Standards and Metrology to jointly create a cross-ministerial cross-ministerial system. Comprehensive cross-disciplinary research project. In 2021, he served as a dual-appointed professor in the Department of Biochemistry and Department of Biomedical Engineering at Tulane University in the United States. His scientific research direction is mainly the research and development of bio-optoelectronics and bio-sensing chips, with a preference for the development of applied technologies, especially in the diagnosis of clinical diseases, IVD, smart medical care, environmental protection and food testing. In terms of disease treatment, it mainly focuses on the diagnosis and treatment of mental diseases and degenerative diseases through biophysical therapy including light, electricity, magnetism, music, etc.

He has received many awards and honors, including the Kauffman Entrepreneurship Professor Award in 2009 and 2011, the 2014 Japan Society for the Promotion of Science Visiting Professor Award, the 2016 American Brain Mapping Association Technology Development Pioneer Award, and the 2016 Minority Serving Institution Teacher Award. Cancer Research Award (awarded by the American Association for Cancer Research (AACR)), and the 2019 IEEE Distinguished Lecturer Award.

By 2023, he has published nearly 190 SCI academic papers, and is the main inventor of 18 international patents. He was the founder and technical director of three start-up companies in China, the United States, and Canada. He has long served as a scientific research project review expert for the National Foundation for Science and Technology of the United States, the National Institutes of Health of the United States, the Ministry of Science and Technology of China, and the National Natural Science Foundation of China, a guide review expert for the Shenzhen Science and Technology Innovation Bureau, and a planning project review expert for the Shenzhen Municipal Works Bureau.

Academic Publications
  1. Z. Zeng, J. Wang, S. Zhao, Y. Zhang, J. Fan, H. Wu, J. Chen, Z. Zhang, Z.Meng, L. Yang, R. Wang, B. Zhang, G.Wang, C.‐Z. Li, G. Zang,  A Bioinspired Flexible Sensor for Electrochemical Probing of Dynamic Redox Disequilibrium in Cancer Cells, Advanced Science, 2023, 2304079.
  2. X. Zhang, Q. Yang, L. Ma, D. Zhang, W. Lin, N. Schlensky, H. Cheng, Y. Zheng, X. Luo, C. Ding, Y. Zhang, X. Hou, F. Lu, H. Yan, R. Wang, C.-Z. Li, K. Qu, Automatically showing microbial growth kinetics with a high-performance microbial growth analyzer, Biosensors and Bioelectronics,2023, 239, 115626.
  3. S. Liu, S. Kumari, H. He, P. Mishra, B.N. Singh, D. Singh, S. Liu, P. Srivastava, C.Z. Li, Biosensors integrated 3D organoid/organ-on-a-chip system: A real-time biomechanical, biophysical, and biochemical monitoring and characterization, Biosensors and Bioelectronics, 2023, 231, 115285.
  4. S.C. Barman, D. Al Sulaiman, X. Wang, Z. Sun, H.N. Alshareef, C.Z. Li, Bioelectrical and biomechanical properties of Extracellular Vesicles-Outlook and Electrochemical Biosensing, Current Opinion in Electrochemistry, 2023, 101311.
  5. W. Zheng, S.M. LaCourse, B. Song, D.K. Singh, M. Khanna, J. Olivo, J Stern, Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
  6. S. Alwarappan, N. Nesakumar, D. Sun, T.Y. Hu, C.Z. Li, 2D metal carbides and nitrides (MXenes) for sensors and biosensors, Biosensors and Bioelectronics 205, 113943,2022.
  7. W. Liu, X. Zhu, M. Mozneb, L. Nagahara, T. Y. Hu, C.-Z. Li, Lighting up ATP in cells and tissues using a simple aptamer-based fluorescent probe. Microchim Acta 188, 352 (2021)
  8. B. Ning, Z. Huang, B. Yungquist, J. Scott, A. Niu, K. Zwezdaryk, C. Bojanowski, J. Cao, N. Saba, X. Yin, J. Fan, C. Lyon, C.-Z. Li, C. Roy C, Y. Hu. Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma. Nat Nanotechnol. 2021. 16 (9), 1039-1044.
  9. T.Y. Hu, P. Amrollahi, W. Zheng, C. Monk, C.-Z. Li, Nanoplasmonic Sensor Approaches for Sensitive Detection of Disease-Associated Exosomes, ACS Applied Bio Materials, 2021, 4 (9), 6589–6603.
  10. L. Liu, F. Yin, Y. Lu, X. Yan, C.C. Wu, X. Li, C.-Z. Li, A light-up “G-quadruplex Nanostring” for label-free and selective detection of MiRNA via duplex-specific nuclease mediated tandem rolling circle amplification. Nanomedicine: Nanotechnology, Biology and Medicine,2021,32, 102339
  11. S. Jain, M. Nehra, R. Kumar, N Dilbaghi, T.Y. Hu, S. Kumar, A. Kaushik, C.Z. Li, Internet of medical things (IoMT)-integrated biosensors for point-of-care testing of infectious diseases, Biosensors and Bioelectronics, 113074, 2021.
  12. M. Ouyang, D. Tu, L. Tong, M. Sarwar, A. Bhimaraj, C.-Z Li, G.L. Coté, D. Di Carlo,A review of biosensor technologies for blood biomarkers toward monitoring cardiovascular diseases at the point of care, Biosensors and Bioelectronics, 112621, 2020.
  13. M Sarwar, J Leichner, GM Naja, CZ Li, Smart-phone, paper-based fluorescent sensor for ultra-low inorganic phosphate detection in environmental samples, M Sarwar, J Leichner, GM Naja, CZ Li, Microsystems & Nanoengineering,2019,5 (1), 56.
  14. M. Mozneb, E. Mirtaheri, A.O. Sanabria, C.-Z. Li, Bioelectronic properties of DNA, protein, cells and their applications for diagnostic medical devices, Biosensors and Bioelectronics, 112441, 2020.
  15. S. S. Mohapatra, R. D. Frisina, S. Mohapatra, K. B. Sneed, E. Markoutsa, C.-Z. Li, S. Santra, S. Daunert, E. Zeynaloo, R. M Gelfand, S. Lenhert, E. S McLamore, Dong Xiang,
  16. X. Li, F. Yin, X. Xu, L. Liu, Q. Xue, L. Tong, W. Jiang, C.-Z. Li, A facile DNA/RNA nanoflower for sensitive imaging of telomerase RNA in living cells based on “zipper lock- and-key” strategy, Biosensors and Bioelectronics 147, 111788, 2020.
  17. M. Mozneb, A.M. Mirza, C.-Z. Li, Non-Invasive Plasmonic-Based Real-Time Characterization of Cardiac Drugs on Cardiomyocytes Functional Behavior, Analytical Chemistry 92 (2), 2244-2250, 2019.
  18. F Yin, L Liu, X Sun, L Hou, Y Lu, Q Xue, T Lin, X Li, C.Z. Li, A facile deoxyuridine/biotin-modified molecular beacon for simultaneous detection of proteins and nucleic acids via a label-free and background-eliminated fluorescence assay, Analyst 144 (18), 5504-5510,2019.
  19. M Sarwar, P Rodriguez, C.Z. Li, Sweat-based in vitro diagnostics (IVD): from sample collection to point-of-care testing (POCT), Journal of Analysis and Testing 3, 80-88,2019.
  20. X. Zhu, M. Sarwar, J.-J. Zhu, C. Zhang, A. Kaushik, C.-Z. Li, Using a glucose meter to quantitatively detect disease biomarkers through a universal nanozyme integrated lateral fluidic sensing platform, Biosensors and Bioelectronics, 2019, 126, 690-696.