Ph.D (The Chinese University of Hong Kong)

MSc (Huazhong University of Science and Technology)

B.Med (Wuhan University of Science and Technology)

Dr. Wang Xia is currently serving as an Assistant Professor (Teaching) in the School of Medicine, CUHK-Shenzhen. She obtained her Ph.D. from the Chinese University of Hong Kong in 2009. From 2010 and 2017, Dr. Wang worked as a Postdoctoral Fellow and Associate Researcher at the Chinese University of Hong Kong and Thomas Jefferson University. She worked as an Assistant Professor at Shenzhen University Medical School prior to joining CUHK-SZ in 2023. Dr. Wang is interested in the interaction of neural crest cells and extracellular matrix during the development of embryonic tissues and organs. She is also focused on studying the pathogenic mechanisms underlying congenital diseases associated with these processes. She has contributed to numerous publications in prestigious scientific journals such as Gastroenterology, Development, Journal of Dental Research, and Developmental Biology et.al. Her research has been supported by multiple grants, including the National Natural Science Foundation of China Youth Program, Guangdong Natural Science Foundation General Program, Shenzhen Science and Technology Innovation Plan, American Heart Association Postdoctoral Fellowship.

1. Wang K, Wang X, Zhang M, Ying Z, Zu Z, Tam KY, Li C, Zhou G, Gao F, Zeng M, Sze SC, Wang X^#, Sha O^#. Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma. International Journal of Molecular Sciences. 2023 Jan 11;24(2):1416. doi: 10.3390/ijms24021416.
2. Lin W*, Gao F*, Wang X*, Qin N, Chen X, Tam K, Zhang C, Zhang M^#, Sha O^#. The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection. Frontiers in Cellular Neuroscience. 2023 Jan 4;16:1006977.
3. Wang X, Liang YL, Zhu Z, Li WQ, Shi B, Deng YQ, Li CM^#, Sha O^#. Fibronectin regulates the 3rd pharyngeal pouch patterning and morphogenesis. Journal of Dental Research. 2022 Mar 8;220345221078775. doi: 10.1177/00220345221078775.
4. Chi H*, Hao Y*, Wang X*, Tang L, Deng YQ, Chen XX, Gao F, Sha O^#, Jin G^#. A Therapeutic Whole-Tumor-Cell Vaccine Covalently Conjugated with a TLR7 Agonist. Cells. 2022 Jun 21;11(13):1986. doi: 10.3390/cells11131986.
5. Huang T, Hou Y, Wang X, Wang L, Yi C, Wang C, Sun X, Tam P, Ngai S, Sham S, Burns A, Chan WY. Direct Interaction of Sox10 With Cadherin-19 Mediates Early Sacral Neural Crest Cell Migration: Implications for Enteric Nervous System Development Defects. Gastroenterology, 162(1):179-192,2022.01. doi: 10.1053/j.gastro.2021.08.029.
6. Tam WY, Wang X, Cheng ASK, Cheung KK. In Search of Molecular Markers for Cerebellar Neurons. International Journal of Molecular Sciences. 2021 Feb 12;22(4):1850. doi: 10.3390/ijms22041850.
7. Warkala M, Chen DY, Ramirez A, Jubran A, Schonning M, Wang X, Zhao H and Astrof S. Cell-Extracellular Matrix Interactions Play Multiple Essential Roles in Aortic Arch Development. Circulation Research,128(3):e27-e44,2021.02.
8. Wang X, Li C, Zhu Z, Yuan L, Chan WY, Sha O^#.  Extracellular Matrix Remodeling During Palate Development. Organogenesis. 2020 Apr 2;16(2):43-60. doi: 10.1080/15476278.2020.1735239.
9. Ying Z, Yang J, Li W, Wang X, Zhu ZY, Jiang WP, Li CM^#, Sha O^#, Astrin: A Key Player in Mitosis and Cancer. Frontiers in cell and developmental biology,8:866,2020.08.
10. Wang X*, Chen D*, Chen K*, Jubran A, Ramirez AJ and Sophie Astrof. Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Developmental Biology. 2017 Jan 15; 421 (2): 108-117. doi: 10.1016/j.ydbio.2016.12.010. doi: 10.1016/j.ydbio.2016.12.010.
11. Xu X, Liang D, Zhang J, Ji X, Hu H, Sun Y, Jiang T, Wang X, Hu P, Xu X, Generation of integration-free induced pluripotent stem cell line (NJMUi001-A) from a phenylketonuria patient. Stem Cell Research, 25, 2017.12.
12. Wang X and Astrof S. Neural crest cell-autonomous roles of fibronectin in cardiovascular development. Development. 2016 Jan 1; 143(1): 88-100. doi: 10.1242/dev.125286.
13. Chen D*, Wang X*, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S. Fibronectin signals through integrin α5β1 to regulate cardiovascular development in a cell type-specific manner.  Developmental Biology. 2015 Nov 15; 407(2): 195-210. doi: 10.1016/j.ydbio.2015.09.016.
14. Liang D, Wang X, Mittal A, Dhiman S, Hou SY, Degenhardt K, Astrof S. Mesodermal expression of integrin a5b1 regulates neural crest development and cardiovascular morphogenesis. Developmental Biology. 2014 Nov 15;395(2):232-44. doi: 10.1016/j.ydbio.2014.09.014.
15. Wang X, Chan AKK, Sham MH, Burns AJ and Chan WY. Analysis of the sacral neural crest cell contribution to the hindgut enteric nervous system in the mouse embryo. Gastroenterology. 2011 Sep, 141 (3), 992-1002. doi: 10.1053/j.gastro.2011.06.002.