YU, Yijng

Lecturer

Education Background

Ph.D. (University of Toronto)
B.MED (Anhui Medical University)

Research Field
Gut microbiome, Dyslipidemia, Metabolic syndrome, skin enzymes and substrates
Email
yuyijing@cuhk.edu.cn
Biography

Dr. Yijing Yu majored in Clinical Medicine and received her Bachelor of Medicine degree from Anhui Medical University, China, in 2005. She received her first Master of Science degree in Parasitology from Anhui Medical University in 2008. She then performed her second Master of Science postgraduate study in Ryerson University, Canada, and Ph.D. study at Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada, respectively. Her graduate research projects included developing new diagnosis kit for Schistosoma japonicum infection, mechanistic investigation of EHEC O157:H7 virulence, and exploring novel substrates for skin Kallikrein 7 enzyme. After earning her Ph.D. in 2017, she performed two rounds of postdoctoral training in two University of Toronto affiliated institutes (Hospital for Sick Children and Sunnybrook Research institute, respectively). Dr. Yijing Yu joined The Chinese University of Hong Kong, Shenzhen as a Lecturer in September of 2022. Currently, her research interests focus on the interactions among diet, gut microbiota and host metabolism, especially in metabolic syndrome.

Academic Publications

1. Horne R*, Yu Y*, Zhang R, Abdalqadir N, Rossi L, Surette M, Sherman P and Adeli K. High fat-high fructose diet-induced changes in the gut microbiota associated with dyslipidemia in the Syrian Hamsters. Nutrients, 2020 Nov 20, 12 (11): 3557 (* Co-first author).

2. Wang SZ, Yu YJ, and Adeli K. Role of gut microbiota in neuroendocrine regulation of carbohydrate and lipid metabolism via the microbiota-gut-brain-liver axis. Microorganisms. 2020 Apr 7; 8(4). doi: 10.3390/microorganisms8040527.

3. Yu Y, Raka F and Adeli K. The role of the gut microbiota in lipid and lipoprotein metabolism. J Clin Med. 2019 Dec 17; 8(12). pii: E2227.

4. Di Paolo CT, Filippou PS, Yu Y, Poda G, Diamandis EP and Prassas I. Screening of chemical libraries in pursuit of kallikrein-5 specific inhibitors for the treatment of inflammatory dermatoses. Clin Chem Lab Med. 2019 Oct 25; 57(11): 1737-1743.

5. Muytjens CMJ, Yu Y and Diamandis EP. Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract. Version 2. F1000Res. 2018 Oct 19. doi: 10.12688/f1000research. 16255.2. eCollection 2018.

6. Muytjens CMJ, Yu Y and Diamandis EP. Discovery of antimicrobial peptides in cervical-vaginal fluid from healthy nonpregnant women via an integrated proteome and peptidome analysis. Proteomics. 2017, 17(21). doi: 10.1002/pmic.201600461.

7. Filippou PS, Farkona S, Brinc D, Yu Y, Prassas I and Diamandis EP. Biochemical and functional characterization of the human tissue kallikrein 9. Biochemical Journal, 2017, 474(14): 2417-2433.

8. Yu Y*, Prassas I*, Muytjens CM and Diamandis EP. Proteomic and peptidomic analysis of human sweat with emphasis on proteolysis, Journal of Proteomics, 2017, 155: 40-48 (* Co-first author).

9. Yu Y, Prassas I, Dimitromanolakis A and Diamandis EP. Novel Biological Substrates of Human Kallikrein 7 Identified Through Degradomics. Journal of Biological Chemistry, 2015, 290 (29): 17762-75.

10. Yu Y, Prassas I and Diamandis EP. 2014. Putative kallikrein substrates and their (patho)biological functions. Biological Chemistry. 2014, 395(9): 931-943.

11. Chinqcuanco F*, Yu Y*, Kus JV, Que L, Lackraj T, Levesque CM, Barnett Foster D. Identification of a novel adhesion involved in acid-induced adhesion of enterohaemorrhagic Escherichia coli O157: H7. Microbiology, 2012, 158: 2399-2407 (* Co-first author).

12. Zheng H, Wu M, Yu YJ, Zheng ZR, Luo QL and Shen JL. Analysis of the soluble antigens of schistosoma japonicum adult worm with two dimensional electrophoresis followed by immunoblotting. Clinical Transfusion and Laboratory Medicine, 2009, 11(2): 107-112.

13. Luo QL, Qiao ZP, Zhou YD, Li XY, Zhong ZR, Yu YJ, Zhang SH, Liu M, Zheng MJ, Bian MH and Shen JL. Application of signaling protein 14-3-3 and 26KDa glutathione-S-transferase to serological diagnosis of schistosomiasis japonica. Acta Tropica, 2009, 112 (2): 91-96.

14. Qiao ZP, Shen JL, Yu YJ, Li X and Yu L. Sag5b: a novel gene for differentiation of strain virulence of Toxoplasma gondii. Chinese Journal of Zoonoses, 2008, 24(3): 189-192.

15. Zhou YD, Luo QL, Yu YJ, Zhang SH, Li J and Shen JL. Detection of circulating antigen of schistosoma japonicum using yolk immunoglobulin-based ELISA. Acta Universitatis Medicinalis Anhui. 2008, 43(4): 372-376.

16. Yu YJ and Shen JL. The regulatory effects of schistosoma infection on supersensitive and autoimmune diseases. Chinese Journal of Microbiology and Immunology. 2007, 27(12): 1155-1159.

17. Yu YJ, Shen JL, Luo QL and Qiao ZP. The combined profile tests of circulating Sj14-3-3 and its antibodies for the diagnosis of schistosomiasis. Acta Universitatis Medicinalis Anhui. 2007, 42(4): 351-354.

18. Luo QL, Wang ZC, Li M, Zheng MJ, Yu YJ, Luo F and Shen JL. Application of indirect ELISA with recombinant signaling protein 14-3-3 of schistosoma japonicum for the immunodiagnosis of schistosomiasis. Chinese Journal of Zoonoses. 2007, 27(3): 231-235.