PhD (University of New South Wales)

Msc (South China Normal University)

Professor Cheng Jiang obtained his PhD degree with honor of double-A level thesis in 2016. After that, he joined the University of Oxford to carry on postdoctoral fellow study. In recent years, his research interest is mainly focusing on clinical disease orientated high/low throughput sensory device based fundamental study, in which he pioneered to develop and apply antifouling immunobneads to isolate high-purity exosomes from large-scale clinical serum samples (n>2000) and emphasized on the follow-up biomarker discovery based translation medicine. His has made milestone progress in the early diagnostic of Parkinson’s disease (PD) with special achivements in developing single biomarker for separation of PD vs HC (AUC=0.86) and dual-marker for separation of PD vs MSA (AUC=0.93). Both of them are the highest world records so far.

To date, He has hosted the John Fell Grant and co-hosted the Michael J. Fox Foundation grant, which manages the largest and most famous PD cohort globally. In 2020, he was awarded the Thomas Wills Early Career Researcher Prize based on his research excellence. He is currently an invited reviewer for more than 10 SCI journals including Chem Comm, J Nanobiotechnology. ACS Chem Neurosci, Sens. Actuator B Chem, Biomacromolecules, Oncology Reports, ACS Appl. Bio Mater, etc. He is also served as guest editor for Photonics、Front. Bioeng. Biotechnol, and the member of Youth Editorial Board of Extracellular Vesicles and Circulating Nucleic Acids (EVCNA).

1. Jiang, C.,* Fu, Y.,  Liu, G., Shu, B., Jason Davis,* George K. Tofaris* (2022). Multiplexed Profiling of Extracellular Vesicles for Biomarker Development. Nanomicro Lett. 14:3 DOI: 10.1007/s40820-021-00753-w (First-author and co-corresponding author)

2. Jiang, C., Hopfner, F, Berg, D, Hu, MT, Pilotto, A, Borroni, B, Davis, JJ, Tofaris, G.* (2021) Validation of α-synuclein in L1CAM-immunocaptured exosomes as a biomarker for the stratification of Parkinsonian syndromes. Mov Disord. 36 (11), 2663-2669 (editor’s choice: featured with infographic, top medical journal)

3. Liu GZ,* Jiang C,* Lin XT, Yang Y. (2021) Point-of-care detection of cytokines in cytokine storm management and  beyond:  significance  and  challenges.  VIEW.  (Co-corresponding author, doi.org/10.1002/VIW.20210003, featured with front-cover image)

4. Jiang, C., Wang, G X., Hein, R., Liu, N Z., Luo, X L.,* & Davis, J J* (2020). Antifouling Strategies for Selective In Vitro and In Vivo Sensing. Chem. Rev. 120, 8, 3852-3889. (Highly cited paper: 2021 Web of Science & Top5 (out of 264) 2020 favorite Chemical Reviews)

5. Zheng, Y.,* Jiang, C., Ng, S. H., Lu, Y., Han, F., Bach, U., & Gooding, J. J.*  (2016). Unclonable Plasmonic Security Labels Achieved by Shadow-Mask-Lithography-Assisted Self-Assembly. Adv. Mater, 28, 2330–2336 (Supervisor is the first author)   

6. Jiang, C, Hopfner, F, Hu. M, Katsikoudi, A, Evetts, S, Huang, Y, Catli, C, Hein, R, Li, K, Davis, JJ & Tofaris, GK* (2020). Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical Parkinsonism. J. Neurol. Neurosurg. Psychiatry 91, 720–729 (top medical journal)

7. Jiang, C., Alam, M. T., Taufik, S., Han F., Fan S. J., & Gooding, J. J,* (2016). Unique sensing interface that allows the development of an electrochemical immunosensor for the detection of Tumor Necrosis Factor α in whole blood. ACS Sens, 1, 1432–1438

8. Fu, Y., Jiang, C., Davis, J,* Tofaris, GK* (2020).  Facile Impedimetric Analysis of Neuronal Exosome Markers in Parkinson’s Disease Diagnostics. Anal Chem. 92, 13647–13651. (Co-first author)

9. Deng, M., Jiang, C., & Jia, L.* (2013). N-methylimidazolium modified magnetic particles as adsorbents for solid phase extraction of genomic deoxyribonucleic acid from genetically modified soybeans. Anal. Chim. Acta, 771, 31–36. (Co-first author)

10. Jiang, C., Alam, M. T., Parker, S. G., Darwish, N., & Gooding, J. J.* (2016). Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryl-Diazonium Salts. Langmuir, 32, 2509–2517.

11. Jiang, C., Alam, M. T; Fan S. J, W. Y. F., Moraes. S., Liu G. Z., & Gooding, J. J,* (2017). Aryldiazonium salt derived mixed organic layers: from surface chemistry to their applications. J. Electroanal. Chem., 15, 265–278. 

12. Jiang, C., Tanzirul Alam, M., Parker, S. G., & Gooding, J. J.* (2015). Zwitterionic Phenyl Phosphorylcholine on Indium Tin Oxide: a Low‐Impedance Protein‐Resistant Platform for Biosensing. Electroanalysis, 27, 884–889.

13. Jiang, C., Xu., S, Zhang., S & Jia, L.* (2012). Chitosan functionalized magnetic particle-assisted detection of genetically modified soybeans based on polymerase chain reaction and capillary electrophoresis. Anal. Biochem, 420, 1, 20-25.

 14. Su, Q;* Jiang, C; Gou, D;* Long, Y.* (2021) Surface plasmon assisted fluorescence enhancing and quenching: from theory to application.  ACS Appl. Bio Mater. 4, 6, 4684–4705  

 15. Kaurab, J., Jiang, C., & Liu. GZ* (2019). Different Strategies for Detection of HbA1c Emphasizing on Biosensors and Point of-Care Analyzers. Biosens. Bioelectron, 123, 1, 85-100.

 16. Cao, CM., Zhang, Y., Jiang, C., Qi, M., & Liu. GZ* (2017) Advances on Aryldiazonium Salt Chemistry Based Interfacial Fabrication for Sensing Applications. ACS Appl. Mater. Interfaces, 9 (6), 5031–5049.

 17. Guan, Y., Jiang, C., Hu, C. & Jia, L* (2010). Preparation of multi-walled carbon nanotubes functionalized magnetic particles by sol–gel technology and its application in extraction of estrogens. Talanta, 83(2), 337-343.

 18. Taufik, S., Barfidokht, A., Alam, M.T., Jiang, C., Parker, S.G. & Gooding, J.J* (2016). An antifouling electrode based on electrode–organic layer–nanoparticle constructs: Electrodeposited organic layers versus self-assembled monolayers. J. Electroanal. Chem, 779, 229-235.

19. Xu, S., Jiang, C., Lin, Y. and Jia, L* (2012). Magnetic nanoparticles modified with polydimethylsiloxane and multi-walled carbon nanotubes for solid-phase extraction of fluoroquinolones. Microchim Acta, 179(3-4), 257-264. 

20. Zhang, X., Li, Q., Jin, X., Jiang, C., Lu, Y., Tavallaie, R., & Gooding, J. J. (2015). Quantitative determination of target gene with electrical sensor. Sci Rep, 5, 12539.

21. Zhang, S., Jiang, C., & Jia, L. (2011). Tetrabutylammonium phosphate-assisted separation of multiplex polymerase chain reaction products in non-gel sieving capillary electrophoresis. Anal Biochem, 408(2), 284-288.

22. Sun, J., Wang, G.,*, Cheng, H., Lia, Q., Han, Y., Jiang, C.,(2022) An antifouling electrochemical aptasensor based on hyaluronic acid functionalized polydopamine for thrombin detection in human serum. Bioelectrochemistry.

23. Huang, S; Jiang, C; Mughal, MJ; Wang, G;  Xing, F (2022) An In Vivo Fluorescence Resonance Energy Transfer-based Imaging Platform for Targeted Drug Discovery and Cancer Therapy. Front. Bioeng. Biotechnol.

24. Liu, G; Jiang, C (2022) Diazonium salts and the related compounds for the design of biosensors. Invited book chapter, the Springer