MU, Jing

Assistant Professor

Education Background

Ph. D. (Nanyang Technological University, Singapore)

Bachelor (Nankai University)

Academic Area
Biological Sciences
Research Field
Nanobiological effects, Biomedical imaging, Fluorescence-guided surgery, Nanomedicine
Email
mujing@cuhk.edu.cn
Biography

Prof. Jing Mu is currently an assistant professor at School of Medicine, The Chinese University of Hong Kong, Shenzhen. She received her Bachelor’s degree from Nankai University and his PhD degree from Nanyang Technological University, Singapore (supervised by Prof. Bengang Xing). In 2019-2020, she worked with Prof. Xiaoyuan (Shawn) Chen at National Institutes of Health (NIH) as a postdoctoral fellow. From 2020 to 2025, She worked as an independent principal investigator (PI) at Peking University Shenzhen Hospital.

Her current research interests include chemical and biological tools for bioimaging or therapeutics, and smart gene/drug delivery systems for a variety of biomedical applications. To date, Prof. Mu has published more than 60 SCI papers in journals including Nat. Commun., Adv. Mater., Chem. Soc. Rev., Angew. Chem. Int. Ed., and Adv. Sci., etc. Her publications have been cited over 3,700 times with an H-index of 29. She also serves as a Youth Editorial Board Member of Exploration, View, and SmartMat, and as Guest Editor for journals such as ACS Appl. Mater. Interfaces, Luminescence and Int. J. Mol. Sci.

Academic Publications
  1. J. Zhao, L. Ren, D. Lan, B Zhan, J. Zhang, J. Mu* and C. He*, Streamlined Construction of Boron-Stereogenic BODIPY Library for Near-Infrared Bioimaging. Nat. Commun. 2025, Accepted.
  2. K. Zhu, Z. Li, J. Cao, Y. Cao, J. Wang, S. Wang, L. Chen, H. Zhou, W. Huang, H. Zou, Q. Li, J. Mu*, J. Song*, Radio-Activated Selenium-Doped Janus Ag/Ag2SexSy Nanoparticles for Precise Cancer NIR-II Fluorescence Imaging and Radiosensitization Therapy. Adv. Sci. 2025, 12, 2417828.
  3. W. Gu, R. Bai, J. Wang, J. Wang, C. Fang, Y. Shi, P. Wang, Q. Wang, W. Bing*, T. Xie*, J. Mu*, Biomimetic Polymersomal Nanoreactors for Hepatocyte-Directed Detoxification in Drug-Induced Liver Injury. Materials Today Bio 2025, 34, 102169.
  4. J. Zeng, H. Li, D. Lan, Y. Shi, J. Wang, Y. Li, H. Shan, N. Hu, J. Song*, J. Mu*, In Situ Diagnosis and Therapy Monitoring of Radiation-Induced Enteritis via Ratiometric NIR-II Fluorescence Imaging. Small 2025, 2504189.
  5. H. Li, J. Zeng, Q. You, M. Zhang, Y. Shi, X. Yang, W. Gu, Y. Liu, N. Hu, Y. Wang, X. Chen, J. Mu*, X-Ray-Activated Nanoscintillators Integrated with Tumor-Associated Neutrophils Polarization for Improved Radiotherapy in Metastatic Colorectal Cancer, Biomaterials 2025, 316, 123031.
  6. D. Lan, Z. Chen, J. Mu*, H. Chen*, Y. Zhao*. Approaches to Radiolabeling Nanobodies for Biomedical Applications, ACS Appl. Mater. Interfaces 2025, 17, 7, 10265.
  7. Y. Peng, H. Liu, M. Miao, X. Cheng, S. Chen, K. Yan, J. Mu*, H. Cheng*, G. Liu*, Micro-Nano Convergence-Driven Radiotheranostic Revolution in Hepatocellular Carcinoma. ACS Appl. Mater. Interfaces 2025, 17 (20), 29047.
  8. K. Zhu, X. Liu, L. Fu, J. Cao, Y. Wu, J. Mu*, J. Song*. NIR-II Ratiometric Optical Theranostic Capsule for In Situ Diagnosis and Precise Therapy of Intestinal Inflammation. ACS Nano 2024, 18, 51, 34912.
  9. R. Zhao, D. Lan, B. Xia, M. Dong, J. Mu*, Y. Zhao*, PET-Based Dual-Modal Probes for In Vivo Imaging Small, 2025, 21, 8, 2409713.
  10. J. Zeng, X. Huang, Y. Yang, J. Wang, Y. Shi, H. Li, N. Hu*, B. Yu*, J. Mu*, Near-Infrared Optogenetic Nanosystem for Spatiotemporal Control of CRISPR/Cas9 Gene Editing and Synergistic Photodynamic Therapy. ACS Appl. Mater. Interfaces 2025, 17, 1, 701.
  11. W. Gu, J. An, Y Li, S Wang, Y Yang, S Li, H Li, G Liu, Kai Li, Y Yin, J. Mu*, X. Chen*. Tuning the Organ Tropism of Polymersome for Spleen-Selective Nanovaccine Delivery to Boost Cancer Immunotherapy. Adv. Mater 2023, 35, 41, 2301686.
  12. L. He, N. Zheng, Q. Wang, J. Du, S. Wang, Z. Wang, Z. Gao, G. Chen, J. Mu*, S. Liu*, X. Chen*. Responsive Accumulation of Nanohybrids to Boost NIR-phototheranostics for Specific Tumor Imaging and Glutathione Depletion-Enhanced Synergistic Therapy. Adv. Sci. 2023. 10, 2205208.
  13. W. Gu, S. Li, Y. Yang, S. Wang, K. Li, Y. Zhao*, J. Mu*, X. Chen*, In Vivo Optical Imaging of Reactive Oxygen Species (ROS)-Related Non-Cancerous Diseases TrAC, Trends Anal. Chem. 2023, 169, 117360.
  14. L. Tong, J. Cao, K. Wang, J. Song, J. Mu*, Lanthanide-Doped Nanomaterials for Tumor Diagnosis and Treatment by Second Near-Infrared Fluorescence Imaging. Adv. Optical Mater. 2023, 12, 2301767.
  15. G. Liu, S. Wang, S. Wang, K. Li, J. Mu*, Y. Shi*. Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy. J. Nanobiotechnol. 2023, 21,151.
  16. H. Li, Y. Zhong, S. Wang, M. Zha, W. Gu, G. Liu, B. Wang, Z. Yu, Y. Wang, K. Li, J. Mu*, X*. Chen*. In Vivo Bioorthogonal Labeling of Rare-Earth Doped Nanoparticles for Improved NIR-II Tumor Imaging by Extracellular Vesicle-Mediated Targeting. Nano Res. 2023, 16, 2895.
  17. S. Li, H. Huo, X. Gao L. Liu*, S Wang, J. Ye, J. Mu*, J. Song *. Engineering Janus Gold Nanorod-Titania Heterostructures with Enhanced Photocatalytic Antibacterial Activity against Multidrug-Resistant Bacterial Infection. Nano Res. 2023, 16, 2049.
  18. J. Mu, C. Li, Y. Shi, G. Liu, J. Zou, D. Zhang, C. Jiang, X. Wang, L, He*, P. Huang*, Y, Yin*, X. Chen*. Protective Effect of Platinum Nano-Antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury. Nat. Commun. 2022, 13, 2513.
  19. Q. Li, L. Liu, H. Huo, L. Su, Y. Wu, H. Lin*, X. Ge, J. Mu*, X. Zhang, L. Zheng, J. Song*. Nanosized Janus AuNR-Pt Motor for Enhancing NIR-Ⅱ Photoacoustic Imaging of Deep Tumor and Pt2+ Ions-Based Chemotherapy. ACS Nano. 2022, 16, 5, 7947.
  20. M. Yuan, X. Fang, Y. Wu, Y. Xu*, H. Feng, J. Mu*, Z. Chen, Y. Lin, Q. Fu, W. Du, H, Yang, J. Song*. Activatable Nanoprobe with Aggregation-Induced Dual Fluorescence and Photoacoustic Signal Enhancement for Tumor Precision Imaging and Radiotherapy. Anal. Chem. 2022, 94 (12),5204.
  21. J. Mu* M, Xiao, Y, Shi, X, Geng, H, Li, Y, Yin*, X. Chen*. The Chemistry of Organic Contrast Agents in the NIR-II Window. Angew. Chem. Int. Ed. 2022, 61, 14, e202114722.
  22. L. He, J. Mu*, X. Chen*. Rationally programming nanomaterials with DNA for biomedical applications. Adv. Sci. 2021, 8, 2003775.
  23. M. Jiang, J. Mu*, O. Jacobson, Z. Wang, L.C. He, J. Qu, P. Huang*, X. Chen*. Reactive Oxygen Species Activatable Heterodimeric Prodrug as Tumor Selective Nanotheranostics. ACS Nano, 2020, 14,16875.
  24. J. Mu, L. He*, W. Fan, W. Tang, Z. Wang, C. Jiang, D. Zhang, Y. Liu, H. Deng, J. Zou, O. Jacobson, J. Qu, P. Huang*, X. Chen*. Cascade Reactions Catalyzed by Planar Metal Organic Framework Hybrid Architecture for Combined Cancer Therapy. Small 2020, 42, 2004016.

     

Patents

  1. 穆婧,黄鹏,一种级联纳米酶及其制备方法与应用,CN 113549611 B
  2. 穆婧,李慧,钟燕凤,王淑敏,一种稀土光学探针及其制备方法与应用,CN 114854415 B
  3. 穆婧,顾文星,杨亚杰,李沈华,一种器官靶向聚合物纳米囊泡系统及其制备方法和应用,CN 115887380 B