Doctor of Medical Imaging (Shantou University)

Master of Psychiatry (Shantou University)

Bachelor of Clinical Medicine (Anhui University of Science & Technology)

Diploma in Clinical Medicine (Anhui Medical University)

Prof. Zhang Jie joined The Chinese University of Hong Kong, Shenzhen in 2025 and currently serves as Assistant Professor (Clinical) in the School of Medicine. He earned his Bachelor’s degree in Clinical Medicine from Anhui University of Science & Technology in 2004, followed by a Master’s degree in Psychiatry and Mental Health (2008) and a Ph.D. in Medical Imaging and Nuclear Medicine (2013), both from Shantou University. He then completed postdoctoral training in Immunopsychiatry at King’s College London, UK.

Prior to joining CUHK-Shenzhen School of MEDICINE, Prof. Zhang accumulated extensive clinical and research experience in adult and adolescent mental health disorders at the Shantou University Mental Health Center (Guangdong Province), Zhongshan Third People’s Hospital (Guangdong Province), and Huainan Fourth People’s Hospital (Anhui Province). He currently serves as Associate Editor for the journal Child and Adolescent Psychiatry and Mental Health.

Prof. Zhang’s research focuses on adolescent depressive disorders, inflammatory biomarkers, and precision intervention strategies. He has led or participated in multiple municipal, provincial, and national research projects, including grants from the National Natural Science Foundation of China, Guangdong Natural Science Foundation, Guangdong Medical Research Foundation, and Zhongshan Public Welfare and Basic Research Program. His work has been published in high-impact journals such as Molecular Psychiatry and Brain, Behavior, and Immunity.

Committed to medical education and translational psychiatry research, Prof. Zhang actively integrates novel technologies and research findings into both teaching and clinical practice.

Selected Publications:

1. Ye Q, Yang Y, Qi Y, Li J, Lei H, Sun L, Zhang J. Global trends and hotspots of adolescent eating disorders: a bibliometric study and visual analysis. Front Psychiatry. 2025 23; 16:1608930. doi: 10.3389/fpsyt.2025.1608930.
2. Zhang J, Zhang Y, Ping J, Luo J, Huang H, Ren Y, Jiang T, Liu X. Prevalence and Correlates of Depressive Symptoms and Cognitive Impairment in Elderly People over 65 Years Old in the Community and Nursing Homes. Alpha Psychiatry. 2025 Feb 28;26(1):38788. doi: 10.31083/AP38788.
3. Ren Y, Zhang S, Huang C, Zhang J, Jiang T and Fang Y (2024) Perceived parental rearing styles and depression in Chinese adolescents: the mediating role of self-compassion. Front. Psychiatry 15:1417355. doi: 10.3389/fpsyt.2024.1417355
4. Ping, J., Wan, J., Huang, C. Yu, J., Luo, J., Xing, Z., Luo, X., Du, B., Jiang, T., Zhang J. DNMT1 SNPs (rs2114724 and rs2228611) associated with positive symptoms in Chinese patients with schizophrenia. Ann Gen Psychiatry 2023. 22, 40. doi.org/10.1186/s12991-023-00466-x
5. Niu Y-M^#, Zhang J^#, Tang H, Cao L-H, Jiang T-Y, Hu Y-Y. Association between DRD2/ANKK1 rs1800497 C > T polymorphism and post-traumatic stress disorder susceptibility: a multivariate meta-analysis. Front. Neurosci.2023. 17:1102573. doi: 10.3389/fnins.2023.1102573
6. Ping J^#, Zhang J^#, Wan J, Huang C, Luo J, Du B, Jiang T. A Polymorphism in the BDNF Gene (rs11030101) is Associated with Negative Symptoms in Chinese Han Patients With Schizophrenia. Front Genet. 202216;13: 849227. doi: 10.3389/fgene.2022.849227.
7. Junjiao Ping^#, Jie Zhang^#, Jing Wan, Ashmita Banerjee, Caiying Huang, Jinming Yu, Tingyun Jiang, Baoguo Du. Correlation of Four Single Nucleotide Polymorphisms of the RELN Gene With Schizophrenia, East Asian Arch Psychiatry, 2021, 31: 112-118
8. Jie Zhang, Yanzhen Ren, Haifeng Huang, Aaron J. Kauera, Yuzhen Liu, Qifeng Du, Tingyun Jiang, Baoguo Du, Timely psychological care for patients with severe mental illness during COVID-19 epidemic, Asian Journal of Psychiatry 52 (2020) 102178.
9. Jie Zhang^#, Huipeng Lu^#, Haiping Zeng^#, Shining Zhang^#, Qifeng Du, Tingyun Jiang, Baoguo Du, The differential psychological distress of populations affected by the COVID-19 pandemic, Brain Behav Immun. 2020, 87: 49–50.
10. Haiyun Xu*, Handi Zhang, Jie Zhang, Qingjun Huang, Zhiwei Shen, Renhu Wu. Evaluation of Neuron-glia Integrity by in vivo Proton Magnetic Resonance Spectroscopy: Implications for Psychiatric Disorders. Neuroscience & Biobehavioral Reviews. 2016 S0149-7634(16)30421-30423. doi: 10.1016/j.neubiorev.2016.09.027.
11. Golam M. I. Chowdhury, Jie Zhang, Monique Thomas, Mounira Banasr, Xiaoxian Ma, Brian Pittman, Linda Bristow, Eric Schaeffer, Ronald Duman, Douglas Rothman, Kevin Behar*, Gerard Sanacora*. Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. Molecular Psychiatry, 2016, doi: 10.1038/mp.2016.34.
12. Fine R, Zhang J, Stevens HE. Prenatal stress and inhibitory neuron systems: implications for neuropsychiatric disorders. Mol Psychiatry. 2014 Jun;19(6):641-51. doi: 10.1038/mp.2014.35.
13. J. Zhang., C.G. Abdallah., Y. Chen., T. Huang., Q. Huang., C. Xu., Y. Xiao., Y. Liu., Y. Ding., R. Wu, Behavioral deficits, abnormal corticosterone, and reduced prefrontal metabolites of adolescent rats subject to early life stress, Neuroscience Letters, 2013, 545(17), 132-137.
14. J. Zhang., Abdallah CG., Wang J., Wan X., Liang C., Jiang L., Liu Y., Huang H., Hong X., Huang Q., Wu R., Xu C*. Upregulation of adenosine A2A receptors induced by atypical antipsychotics and its correlation with sensory gating in schizophrenia patients, Psychiatry Research, 2012, 200 (2-3), 126-132.