Founding Dean
Founding Dean
Professor Davy Cheng is the Founding Dean of Medicine and Presidential Chair Professor, School of Medicine at the Chinese University of Hong Kong, Shenzhen, China beginning on July 1st, 2021. He received his BSc (Hon) in Biochemistry at the University of Ottawa in 1977 and completed his MSc in Biochemistry at Western University in 1979. He graduated from the Faculty of Medicine (with an Honor Award from the Medical Society), University of Toronto in 1983, and became the Fellow of the Royal College of Physicians and Surgeons of Canada (RCPC) in 1987. In 2007, Prof. Cheng became the first anesthesiologist inducted as a Fellow of the Canadian Academy of Health Sciences (CAHS) in recognition of his great accomplishment and achievement in the academic health sciences in Canada. In 2013, Prof. Cheng was awarded as a Fellow of the Royal Society of Medicine, United Kingdom and was designated as CCPE (Canadian Certified Physician Executive) by the Canadian Medical Association (CMA) and the Canadian Society of Physician Executives (CSPE). Then in 2014, he was honored with the CSPE Excellence in Medical Leadership Award and became Honorary Fellow, Deutsche Gesellschaft fur Anasthesiologie und Intensivmedizin (DGAI). In 2022, he was honored as Honorary Fellow, The Hong Kong College of Anaesthesiologists (HKCA).
Prof. Cheng is a globally recognized healthcare leader at the forefront of research, practice and healthcare policy in the fields of perioperative surgical and anesthesia care, cardiac surgery, critical care medicine, and evidence-based clinical decision-making. Since 2022, he has been twice listed in the World Top 2% Scientists list and has been featured in both the Career-long Impact Rankings and the 2021 Single-year Impact Rankings. His pioneer work in fast-track cardiac anesthesia and recovery has become the standard of cardiac anesthesia and recovery practice around the world. As Principal Investigator or co-investigator since faculty appointment, Prof. Cheng has been awarded over CAD 16.1M total in peer-reviewed and non-peer-reviewed grants. He has published over 170 peer-reviewed scientific papers in high-impact journals and 60 books/chapters (citations 24081, h-index 68, i10-index 148). Prof. Cheng has broad international experience, he served on several international committees, organizations and Editorial Boards, including anesthesia (CJA), cardiothoracic and vascular anesthesia (JCTVA) and cardiac surgery (INNOVATIONS). Moreover, Prof. Cheng was the co-founder and Medical Director of the MEDICI Centre (Medical Evidence, Decision Integrity & Clinical Impact), which was a World Health Organization (WHO) designated Collaborating Center in the study of global perioperative surgery and anesthesia care. In addition, he was elected as President of the Association of Canadian University Departments of Anesthesiology (ACUDA), Chair of Board of Trustees, International Anesthesia Research Society (IARS), as well as the President of the Association of Cardiac Anesthesiologists (ACA), Co-Chair of Steering Committee and Expert Consensus Panel for the International Society for Minimally Invasive Cardiac Surgery (ISMICS), the European Association of Cardiothoracic Society (EACTS), and the World Health Organization (WHO) in practice guideline development. Prof. Cheng also has been invited as visiting professor, named lecturer and guest speaker to over 180 Universities, Cardiac Centers and nationally/internationally conferences.
Executive Associate Dean
Executive Associate Dean
Prof. Tsui completed his medical training at Dalhousie University, Halifax, in 1995 after obtaining his Masters of Science in Pharmacy in 1991. These degrees followed a Diploma in Engineering and Bachelors of Science in both Mathematics and Pharmacy. Prof. Tsui completed his anesthesia residency training at the University of Alberta Hospital in Edmonton in 2000, and he received further experience in pediatric anesthesia at British Columbia Children's Hospital in Vancouver. After 16 years of practice at the University of Alberta Hospital and Stollery Children’s Hospital, Prof. Tsui was recruited to Stanford University in 2016.
Currently, Prof. Tsui is a University Medical Line Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine at Stanford University. In his position as an adult and pediatric anesthesiologist at the Stanford University Medical Center and the Lucile Packard Children’s Hospital, he specializes in regional anesthesia techniques.
Prof. Tsui is an avid and internationally recognized researcher in many areas of regional anesthesia. During his residency, Prof. Tsui developed an interest in improving the accuracy of epidural catheter placement and was issued a U.S. patent in relation to his research. Prof. Tsui has expanded his research into the use of ultrasound in regional anesthesia, with particular relevance to peripheral nerve block performance. Prof. Tsui is also responsible for development of the E-Catheter catheter-over-needle kit for use during peripheral nerve blocks. The primary objective of his research is to transform regional anesthesia from an “art” into a reliable and reproducible “science” by further exploring the basic scientific and clinical aspects of electrophysiological signal monitoring and integrating this with the latest advances in ultrasound.
Academically, Prof. Tsui received the 2005 John Bradley Young Educator Award from the Canadian Anesthesiologists' Society. This award recognizes his work as a clinical educator, researcher, and anesthesia trainee role model. While in Canada, Prof. Tsui was the only Canadian invited to write a chapter for a prestigious American anesthesia textbook-Clinical Anesthesia (Barash). Prof. Tsui wrote the first textbook on Ultrasound-and Nerve Stimulation-Guided Regional Anesthesia. It's become the main reference for anesthesiologists who are interested to use ultrasound in regional anesthesia. This work was translated to Korean. Prof. Tsui also co-authored the first pediatric textbook on the subject, the Pediatric Atlas of Ultrasound-and Nerve Stimulation-Guided Regional Anesthesia. This work has also been translated to Chinese and received positive reviews. In addition, Prof. Tsui co-authored and edited "Principles of Airway Management" and "Complications in Regional Anesthesia." From 2006 to 2018, Prof. Tsui served on the editorial board of the Canadian Journal of Anesthesia. Prof. Tsui is currently the editor of the journal of Regional Anesthesia and Pain Medicine.
Prof. Tsui has received the Alberta Heritage Foundation for Medical Research (AHFMR) Clinical Scholar award and has previously received research awards and grants from the Canadian Institutes of Health Research (CIHR), Canadian Anesthesiologists’ Society, AHFMR, and University of Alberta. In 2015, a prestigious award, the CAS Research Recognition Award, was presented by the Canadian Anesthesiologists’ Society to Prof. Tsui "in recognition of significant research contributions to regional anesthesia, acute pain management and pediatric anesthesia in Canada and around the world". In 2022, the American Society of Regional Anesthesia and Pain Medicine (ASRA) awarded Prof. Tsui, the Distinguish Service Award. This prestigious annual award has been presented to honor persons who have made remarkable contributions to the field of regional anesthesia and pain medicine.
Associate Dean (Faculty Affairs)
Associate Dean (Faculty Affairs)
Dr. Yuxin Yin is the Professor of Cancer Biology, Presidential Chair Professor, Chinese University of Hong Kong (Shenzhen) School of Medicine. Dr. Yin received his M.D. from the Peking Union Medical College and his Ph.D. from the University of North Carolina at Chapel Hill, USA. He conducted his postdoctoral training in Princeton University. In 1999, he was appointed as a tenure-track assistant professor in the Department of Radiation Oncology in the College of Physicians and Surgeons, Columbia University and was promoted to an associated professor with tenure in 2007. Dr. Yin’s research field is cancer biology with main focus on tumor suppressors p53 and PTEN in cell cycle regulation, apoptosis and genomic stability. In 1992, he reported a fundamental role for p53 in controlling the G1 checkpoint and maintaining genomic stability (Cell, 1992). In 1998, he found that p53 is required for the cellular apoptotic response to oxidative stress (Nature, 1998). In 2003, his team at Columbia demonstrated that PAC1 phosphatase is a direct transcriptional target of p53 in signaling apoptosis and tumor suppression, establishing a link between p53 and the MAP kinase cascade (Nature, 2003). In 2007, his group reported that PTEN plays a fundamental role in the maintenance of chromosome stability and that PTEN does so through physical interaction with centromeres (Cell, 2007). In 2015, his group revealed a new mechanism for DNA replication (Cell Research, 2015) and demonstrated that PTEN could controls the DNA replication process in response to replicative stress (Cell Reports, 2015). His group revealed a novel mechanism of alternative translation of protein and discovered some new members of the PTEN protein family named PTENα (Cell Metabolism, 2014), PTEN β (Nature Communications, 2017) and PTENε (EMBO, 2021). They also found that PTENα protein plays an important role in regulating the chemotaxis of neutrophils (Blood, 2019). In addition, they found PTEN is methylated by PRMT6 at arginine residue in modulation of pre-mRNA splicing (PNAS, 2019). These studies provide new insights into the mechanisms by which the PTEN family maintains genomic stability, suppresses tumorigenesis and development. In the field of immunity, they found that PAC1/DUSP2 phosphatase dephosphorylates STAT3 and modulates TH17 development in inflammatory disease (Nature Immunology, 2015). They also reported for the first time that PAC1, as a negative regulator of the immune system, specifically inhibits the defense function of T lymphocytes and promotes tumor immune escape (Nature Immunology, 2020). In addition, they revealed that PTENα functions as an immune suppressor and promotes immune resistance in PTEN-mutant cancer (Nature Communications, 2021). In translational medicine, his group isdeveloping AI aided metabolomic methods to detect early stage of cancers (Science Advances, 2021; Science Translational Medicine, 2021). His team has also developed several new small molecule chemical compounds to inhibit tumor growth, or activate the immune system to kill tumor cells, and promote tumor immunotherapy.
Associate Dean (Medical Education)
Associate Dean (Medical Education)
Professor Michael Tam received his undergraduate and postgraduate degrees at the University of Toronto, Canada. He joined CUHK in 1981 as a founding member of the Faculty of Medicine and retired in 2012. During this 31 years, He served as Chairman of the Department of Physiology, Associate Director (Medical Education) of the School of Biomedical Sciences, and Associate Dean (Student Affairs) of the Faculty of Medicine. After retirement, he continues to teach various medical courses and coordinate and teach the Physiology Course at both undergraduate and postgraduate levels of the Nethersole School of Nursing CUHK.
Professor Tam’s research areas included genetic adaptation in high altitude. He studies the genetic difference between Tibetans and Hans and looks for genes contributing to better survival at high altitude. Professor Tam’s team is the first group to identify the natural selection of the gene EPAS1 that enables Tibetans to better adapt to high altitude. Professor Tam is also deeply committed in examining the mechanism of trichosanthin action. Trichosanthin is a type I ribosome-inactivating protein with antiviral activity. It inhibits replication of human immunodeficiency virus (HIV) as well as herpes simplex virus (HSV). The mechanism is unknown. Found results support the hypothesis that trichosanthin selectively induces apoptosis in viral infected cells while sparing uninfected cells. Infected cells die prematurely and therefore limit viral replication. The mechanism appears to involve the MAPK signal pathway.
Associate Dean (Postgraduate Studies)
Associate Dean (Postgraduate Studies)
Prof. Ye graduated from Shanghai Second Medical College in 1982, and obtained his PhD degree from Washington University in St. Louis in 1988. Since 1989, he started his independent research from assistant professor to full professor at The Scripps Research Institute and University of Illinois College of Medicine. His main research directions include G protein-coupled receptors and their signaling functions in innate immune cells, mechanisms of inflammation and pathological models, and anti-inflammatory drug targets. He has collaborated with Johnson & Johnson, Novartis and GSK, and obtained 2 U.S. patents and 2 Chinese patents as first inventor, and 2 other patents as co-inventor. Prof. Ye has published 230 SCI papers that have been cited for more than 20,000 times. He served as Chair Professor and Dean of School of Pharmacy at Shanghai Jiao Tong University (2010-2014) and Chair Professor at University of Macau (2015-2019). Prof. Ye joined The Chinese University of Hong Kong, Shenzhen in February 2019 to establish School of Life and Health Sciences. In 2020 he led the effort of establishing the CUHK(SZ) Futian Biomedical Innovation R&D Center. Prof. Ye was elected Excellent Teacher of Shenzhen in 2021, and received Outstanding Research Award of CUHK(SZ) in 2022. In recent years he has been on the lists of Clarivate Highly Cited Researcher (2018-2020, 2022), Stanford World's top 2% Scientist (2020-2023), and Elsevier’s Most Cited Chinese Researchers (2022). Among the academic services he provided are Associate Editor of The FASEB Journal, Associate Editor of Pharmacological Reviews, and Editorial Boards of Molecular Pharmacology and British Journal of Pharmacology.
Associate Dean (Addmissions & Student Affairs)
Associate Dean (Addmissions & Student Affairs)
Prof. Hsien-Da Huang is a presidential chair professor and Associate Dean of student affairs at the School of Medicine, and the Executive Director of Warshel Institute of Computational Biology, The Chinese University of Hong Kong, Shenzhen. He received Ph.D. at Department of Computer Science and Information Engineering, National Central University, Taiwan, in 2003. He was a tenured professor, distinguished professor, chair professor and vice dean at the College of Biological Science and Technology, National Chiao Tung University, Taiwan. During 2009-2016, he was the Chairman at Department of Biological Science and Technology, NCTU. He was the President of Taiwan Society of Bioinformatics and Systems Biology (2014-2017).
Prof. Huang’s research group majorly focuses on biological multi-disciplinary research topics, including Bioinformatics, Genomics, Metagenomics & Microbiome, Intelligent Biomedical Technologies (Drug Development, Genetic Test, & Precision Medicine), AI & Machine Learning, and Biological Database Design & Development. He published more than 200 peer-reviewed publications, mostly in prestigious journals, including Science, Molecular Cell, Circulation, The Journal of Clinical Investigation, PLoS Biology, Hepatology, Cancer Research, and Nucleic Acids Research. He published 15 highly-cited papers, more than 45 papers with 10.0 or higher impact factor, an h-index of 68, and more than 13377 citations in Google Scholar.
Prof. Huang was selected for Highly Cited Researcher 2019 by Web of Science. He received several honors such as the Outstanding Research Award (2010 and 2015) and Ta-You Wu Memorial Award (2009) of the Ministry of Science and Technology, Taiwan.
Associate Dean (Hospital Affairs)
Associate Dean (Hospital Affairs)
Professor Guangjun YU, Doctor, Researcher, PhD supervisor; Associate Dean of the School of Medicine of the Chinese University of Hong Kong, Shenzhen; President of National Health Data Institute, Shenzhen; President of Shenzhen Longgang District People's Hospital (the second affiliated to School of Medicine of the Chinese University of Hong Kong, Shenzhen); Head of Medical Information Institute of China Hospital Development Institute, Shanghai Jiao Tong University; Vice President of Pediatric Branch of Shanghai Medical Doctor Association; Vice president of Shanghai Women and Children Research Association; Chairman of Shanghai Medical Association Internet Medical Branch; Standing Committee of Pediatric Branch, and Deputy Chairman of the children health care Special Committee of Chinese Medical Doctor Association; Vice Chairman of Big Data Quality Committee of China Health Information Society; Vice Chairman of Internet Medical Committee of China Medical Information Society. Top 10 of The 4th Session Shanghai Youth Medical Manager.
Assistant Dean (Research & Innovation)
Assistant Dean (Research & Innovation)
Prof. Yang Du obtained PhD degree from the University of Science and Technology of China, and then went to Stanford University for postdoctoral training. During this period, he was awarded a full post-doctoral fellowship sponsored by the American Heart Association. He was also offered with the position of tenure-track Assistant Professor in the School of Medicine at the University of Michigan, Ann Arbor. His main research centers on the structure, function and drug discovery of G protein-coupled receptor (GPCR). Professor Du has published nearly 80 high-quality SCI papers, including Cell, Science, Nature, Nature Comm, Science Adv, Cell Research and JACS as corresponding author. He is currently an associate professor and assistant dean in the School of MEDICINE at the Chinese University of Hong Kong, Shenzhen, and a principal investigator in the Kobilka Institute for Innovative Drug Discovery.
Assistant Dean (Postgraduate Studies)
Assistant Dean (Postgraduate Studies)
Prof. Gang CHEN is an Associate Professor in the School of MEDICINE, The Chinese University of Hong Kong, Shenzhen. He received his B.S. degree in Chemistry at the University of Science and Technology of China (USTC) in 2001. He did his Ph.D. studies with Prof. Douglas TURNER in the Department of Chemistry at the University of Rochester. His Ph.D. work involved thermodynamic and NMR studies of RNA internal loops. A better understanding of the sequence dependence of thermodynamics for RNA structures will improve the accuracy of the RNA secondary structure prediction programs such as MFOLD and RNAstructure. He earned his Ph.D. in 2005. He was a postdoctoral fellow in Prof. Ignacio TINOCO’s lab in the Department of Chemistry at the University of California, Berkeley from January 2006 to June 2009. His research in TINOCO lab was on single-molecule mechanical unfolding and folding of RNA pseudoknots by laser optical tweezers, which provided new insights into ribosomal reading-frame regulation by cis-acting mRNA structures. He was a Research Associate in Prof. David MILLAR's lab in the Department of Molecular Biology at The Scripps Research Institute working on HIV-1 Rev-RRE assembly using single-molecule fluorescence techniques. In July 2010, he joined the faculty in the Division of Chemistry and Biological Chemistry at Nanyang Technological University in Singapore. He joined CUHK-Shenzhen in 2020.
His team has been focused on (1) using biophysical and biochemical methods (including single-molecule manipulation using high-resolution optical tweezers) for probing the molecular interactions accounting for the structures, stabilities, dynamics, and functions of RNAs and RNA-ligand complexes; and (2) developing RNA structure-targeting programmable chemically modified peptide nucleic acids (PNAs) and other functional molecules as chemical probes, diagnostic tools, and therapeutic drugs. The team’s high-impact research on targeting RNA duplexes has generated significant interests in the RNA community. The team has been invited to contribute to (1) a review article on RNA triplexes in the journal Wiley Interdisciplinary Reviews: RNA, (2) a book chapter (published by Springer) on recognition and targeting of mature miRNA and miRNA hairpin precursor by duplex and triplex formation, respectively, (3) a methods article for the Journal of Visualized Experiments on sequence-specific and selective recognition of double-stranded RNAs over single-stranded RNAs by chemically modified peptide nucleic acids, (4) a News & Views article for the journal Nature Chemical Biology on the importance of base triples, junctions, and other non-Watson-Crick interactions in facilitating catalytic reactions of an RNA enzyme, and (5) an article in the Future of Biochemistry special issue in the journal Biochemistry (invited by the Editor-In-Chief, Prof Alanna Schepartz). The interdisciplinary team welcomes talents to join us to probe and target RNA sequences and structures with the ultimate goals of developing modern biological tools, disease diagnosis methods, and precision medicines.
Acting Assistant Dean (Clinical Education)
Acting Assistant Dean (Clinical Education)
Prof. Siu graduated from the Chinese University of Hong Kong and the University of Sydney. After completion of her specialist training in Otorhinolaryngology, Dr. Siu pursued a sub-specialty training in paediatric ear, nose and throat surgery.
Prof. Siu identifies herself as a socialist, feminist and environmentalist. She lives by a motto “兒無階,盡展能” (to aid all children reaching their potentials regardless of their backgrounds). Dr Siu is passionate about mentoring female students and young professionals in bid for gender equality in medical profession.
Assistant Dean (Education)
Assistant Dean (Education)
Prof. Juan DU received her Bachelor Degree of Clinical Medicine from School of Medicine at Jiamusi University in 2000 and Master Degree of Physiology from Anhui Medical University in 2004. Afterwards Prof. Du went to the Health Science Center at the University of North Texas from 2005 to 2006 as a visiting scholar. Prof. Du earned her Ph.D. from the School of Biomedical Sciences at The Chinese University of Hong Kong in 2011. From 2004 to 2020, Prof. Du served as Professor in Physiology, Vice Dean in School of Basic Medical Science, Director of The National Simulation Experimental Center in Basic Medicine, in Anhui Medical University. In 2020, Prof. Du joined The Chinese University of Hong Kong, Shenzhen and contributed to the preparation of School of Medicine. Currently, she is an Assistant Professor and appointed as Assistant Dean (Education) in School of MEDICINE.
Prof. Du’s research mainly focus on calcium signal and cell function, mechanism of tumor exosome secretion, exosome and early diagnosis of tumor, targeted delivery of exosomes and so on. She has presided 4 projects of National Natural Science Foundation of China and 10 provincial scientific research projects. She has also published over 60 academic papers on SCI journals including JASN, Hypertension, etc. Dr. Du has granted High-level Professionals of Longgang Distrcit, Shenzhen. Prof. Du has also won a Third Prize of Science and Technology Achievement Award in Anhui Province. Additionally, she is committed to the medical education, teaching reform and the cultivation of students’ innovation ability. Prof. Du has presided over 8 teaching projects, including the Ministry of Education industry-university cooperative education project, provincial educational reform project and provincial MOOC demonstration project. Prof. Du has granted the title of Famous Teacher of Anhui province, won 3 provincial teaching achievement awards and published over 20 teaching research articles. She has participated as chief editor, deputy chief editor and editorial board member in editing 7 textbooks, including “Refined Physiology” ESP digital textbook, “Physiology”, “Basic Medicine Integrated Experiments” etc. She has also instructed the undergraduate students to obtain nearly 20 national and provincial awards, including the second place of the International Competition of Medical Physiology Knowledge and the champion of the domestic competition, the bronze prize of the National Competition and the champion of the Provincial Competition of Internet + University Students’ Innovation and Entrepreneurship Competition.